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Recent Publications

1. Garrud TAC, Bell B, Mata-Daboin A, Peixoto-Neves D, Collier DM, Corcero-Morales J and Jaggar JH. WNK Kinase is a vasoactive chloride sensor in endothelial cells. Proc Natl Acad Sci USA 2024 Apr 9;121(15):e2322135121. doi: 10.1073/pnas.2322135121.

2. Mata-Daboin A, Garrud TAC, Fernandez-Pena C, Peixoto-Neves D, Leo MD, Bernardelli AK, Singh P, Malik KU, Jaggar JH. Vasodilators activate the anion channel TMEM16A in endothelial cells to reduce blood pressure. Science Signaling 2023 Nov 14;16(811):eadh9399. doi: 10.1126/scisignal.adh9399.

3. Peixoto-Neves D, Yadav S, MacKay CE, Mbiakop UC, Mata-Daboin A, Leo MD, Jaggar JH. Vasodilators mobilize SK3 channels in endothelial cells to produce arterial relaxation. Proc Natl Acad Sci U S A. 2023 Aug;120(31):e2303238120. doi: 10.1073/pnas.2303238120.

4. Garrud TAC, Jaggar JH. STIMulating blood pressure. Elife. 2022 Mar 24;11:e77978. doi: 10.7554/eLife.77978.

5. MacKay CE, Floen M, Leo MD, Hasan R, Garrud TAC, Fernández-Peña C, Singh P, Malik KU, Jaggar JH. A plasma membrane-localized polycystin-1/polycystin-2 complex in endothelial cells elicits vasodilation. Elife. 2022 Mar 1;11:e74765. doi: 10.7554/eLife.74765.

6. Leo MD, Peixoto-Nieves D, Yin W, Raghavan S, Muralidharan P, Mata-Daboin A, Jaggar JH. TMEM16A channel upregulation in arterial smooth muscle cells produces vasoconstriction during diabetes. Am J Physiol Heart Circ Physiol. 2021 Mar 1;320(3):H1089-H1101. doi: 10.1152/ajpheart.00690.2020.

7. MacKay CE, Leo MD, Fernández-Peña C, Hasan R, Yin W, Mata-Daboin A, Bulley S, Gammons J, Mancarella S, Jaggar JH. Intravascular flow stimulates PKD2 (polycystin-2) channels in endothelial cells to reduce blood pressure. Elife. 2020 May 4;9:e56655. doi: 10.7554/eLife.56655.

8. Hasan R, Leo MD, Muralidharan P, Mata-Daboin A, Yin W, Bulley S, Fernandez-Peña C, MacKay CE, Jaggar JH. SUMO1 modification of PKD2 channels regulates arterial contractility. Proc Natl Acad Sci U S A. 2019 Dec 26;116(52):27095-27104. doi: 10.1073/pnas.1917264116.

9. Bulley S, Fernández-Peña C, Hasan R, Leo MD, Muralidharan P, Mackay CE, Evanson KW, Moreira-Junior L, Mata-Daboin A, Burris SK, Wang Q, Kuruvilla KP, Jaggar JH. Arterial smooth muscle cell PKD2 (TRPP1) channels regulate systemic blood pressure. Elife. 2018 Dec 4;7:e42628. doi: 10.7554/eLife.42628.

10. Leo MD, Zhai X, Yin W, Jaggar JH. Impaired Trafficking of β1 Subunits Inhibits BK Channels in Cerebral Arteries of Hypertensive Rats. Hypertension. 2018 Sep;72(3):765-775. doi: 10.1161/HYPERTENSIONAHA.118.11147.

More publications are available at this link:

https://pubmed.ncbi.nlm.nih.gov/?term=Jaggar+JH&sort=date&size=100